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Search Result

Search Results for " ip 10 "

Targets

Hedgehog/Smoothened

13

Compounds

1

Natural Products

10

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T23027 MRT-10 Hedgehog/Smoothened
MRT-10 is a Smoothened (Smo) receptor antagonist.
T8316 1V209 TLR7 agonist T7 TLR
1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.
TP1896L1 Kisspeptin 234 acetate(1145998-81-7 free base) GPR , Kisspeptin
Kisspeptin 234 acetate(1145998-81-7 free base) is a Kisspeptin receptor (KISS1, GPR54) antagonist; a Kisspeptin-10 analogue. It inhibits the stimulation of inositol phosphate (IP) (IC50 = 7 nM) and the release of gonadot...
T76741 Eldelumab BMS-936557,MDX-1100 CXCR
Eldelumab (BMS-936557) is a humanized anti-IP-10 IgG type 1 monoclonal antibody with inhibitory activity against CXCL10.Eldelumab has anti-inflammatory activity and selectively binds to CXCL10 and can be used in the stud...
T10297L AMG 487 CXCR
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.
TP1896 Kisspeptin 234
Kisspeptin 234 is a kisspeptin receptor (KISS1, GPR54) antagonist; kisspeptin-10 analog. Inhibits kisspeptin-10 stimulation of inositol phosphate (IP) (IC50 = 7 nM) and release of gonadotrophin-releasing hormone (GnRH).
T74908 ODN 2336
ODN 2336, an A-Class CpG oligodeoxynucleotide (ODN), serves as a potent TLR9 agonist. It effectively induces IFN-α production and up-regulates IP-10 and IL-18 mRNA expression, leveraging its role as a vaccine adjuvant [1...
T22477 (±)-AMG 487 Others
AMG 487 is an effective and selective antagonist of chemokine receptor 3. AMG 487 inhibited CXCR3-mediated cell migration induced by three CXCR3 chemokines, IP-10, ITAC and MIG (IC50: 8, 15 and 36 nM, respectively).
T29907 Alprostadil sodium PGE1 sodium salt,Prostaglandin E1 sodium
Alprostadil sodium is a prostaglandin receptor ligand with Ki values of 36, 10, 1.1, 2.1, and 33 nM for EP1, EP2, EP3, EP4, and IP, respectively, in mice.It induces vasodilatation and inhibits platelet aggregation, and i...
T38159 STING Agonist 12b
STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 ...
T71764 YM 298198 Hydrochloride
YM 298198 Hydrochloride is a non-competitive antagonist with high affinity and selectivity for mGlu1 receptors (Ki = 19 nM). YM 298198 Hydrochloride is inactive at other mGlu receptor subtypes (mGlu2-7), ionotropic recep...
T36254 DTAGV-1 hydrochloride
Hydrochloride salt of dTAGV-1. Suitable for use in vivo. Following ip administration of 10 mg/kg in mice: T = 4.43 h; Cmax = 2123 ng mL-1; AUCinf = 18517 hr*ng mL-1 and CL = 9.05 mL min-1 kg-1 Negative control dTAGV-1-...
T81311 RASP-IN-1
RASP-IN-1 (Compound A), a lipophilic compound, serves as an inhibitor for macular degeneration and exhibits biological activity within the rabbit retina. In a mouse model [1], the administration of 14 C-RASP-IN-1 (10 mg/...
Cat No. Product Name Synonyms Targets
T1626 Prostaglandin E1 PGE1,Alprostadil Endogenous Metabolite , Prostaglandin Receptor
Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...

Natural Products

Prostaglandin E1
T1626
Synonym: PGE1,Alprostadil
Target: Endogenous Metabolite, Prostaglandin Receptor

Recombinant Proteins

Species：
Human (7)
Cynomolgus (1)
Mouse (1)
Rat (1)
Expression System：
E. coli (5)
HEK293 Cells (4)
P. pastoris (Yeast) (1)
Tag：
C-hFc (2)
His (2)
C-His (1)
C-hFc-6xHis (1)
N-6xHis-GST (1)
N-6xHis-KSI (1)
N-His (1)
Tag Free (1)
Cat No. Product Name Species Expression System
TMPY-02970 CXCL10 Protein, Human, Recombinant Human E. coli
CXCL10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.8 kDa and the accession number is P02778.
TMPY-04943 CXCL10 Protein, Rat, Recombinant (His) Rat P. pastoris (Yeast)
CXCL10 Protein, Rat, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10 kDa and the accession number is P48973.
TMPK-01269 CXCL10 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for leukocyte trafficking and act on tissue cells, like endothel...
TMPJ-00008 CXCL10 Protein, Human, Recombinant (hFc & His) Human HEK293 Cells
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CX...
TMPH-02612 CXCR3 Protein, Mouse, Recombinant (His & KSI) Mouse E. coli
Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell c...
TMPH-01162 CXCR3 Protein, Human, Recombinant (GST & His) Human E. coli
CXCR3 Protein, Human, Recombinant (GST & His) is expressed in E. coli.
TMPY-02300 BIN1 Protein, Human, Recombinant (His) Human E. coli
Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicat...
TMPY-01751 DR3/TNFRSF25 Protein, Human, Recombinant (hFc) Human HEK293 Cells
DR3/TNFRSF25 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.
TMPY-00961 ADAM15 Protein, Human, Recombinant (His) Human HEK293 Cells
ADAM15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54 kDa and the accession number is Q13444-10.
TMPY-05760 DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated Human HEK293 Cells
DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.
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